Ok, a typical problem with XAMPP is that it keeps throwing errors on the screen that should be in the logs only. So if you can turn off display_errors in php.ini it would help.
Then track your errors in suitecrm.log and errors.log (or php_errors.log, whatever your web server log is called) and focus on ERROR and FATAL messages, and try to get a sense of the timestamps, to match the log messages with what you were doing at the time (configuring email / Sending / etc).
Then with this extra information we can try narrowing down what the problem could be…
Hi I did what did you tell me about display_errors and now the errors dont show into email seccion.
and Now the message errors only i found the error in suitecrm.log = Thu Oct 11 17:22:01 2018 [FATAL] ERROR: rmdir_recursive(): argument cache/upgrades/temp/6A96.tmp is not a file or a dir.
The archive errors.log or php_errors.log I couldnt find it, but in Admin-System Settings - View Log- All show = Wed Oct 17 19:56:14 2018 [FATAL] log call at: modules/Administration/index.tpl:53 - MY_FRAME is not set