Compose new email to target list

Good morning,
I started doing my first campaigns. Contacts have been out of the countryside, not sent as “Suppressed by Address or Domain”. Why?

I created a new target list with these contacts and wanted to send them the email out of the campaign. Is there the possibility of compose to new email and as a destinator to enter this “target list”?
Thank you

Can you please elaborate on your problem/requirement in detail with screenshots?