We have the outgoing email config for notices however each user when clicking on email address on an account or contact, will populate the From address as the system address but we have checked and yes each users individual config is correct and when agents see the from email as the system we want it to go from the actual users email acct not the system plus even when we click send to see if it actually goes from the system address as indicated or the user we get this message Error Sending Email. Please contact your administrator for assistance.
Hi, welcome to the Community! 
What is your SuiteCRM version, please?
Do you see any errors in your logs?